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This is mostly done with the small amounts of cocaine remaining on a surface after insufflation (snorting).Another oral method is to wrap up some cocaine in rolling paper and swallow (parachute) it.Second, capillaries in the mouth and esophagus constrict after contact with the drug, reducing the surface area over which the drug can be absorbed.Nevertheless, cocaine metabolites can be detected in the urine of subjects that have sipped even one cup of coca leaf infusion.
Physiological and psychotropic effects from nasally insufflated cocaine are sustained for approximately 40–60 minutes after the peak effects are attained.
The efficiency of absorption of orally administered cocaine is limited by two additional factors.
First, the drug is partly catabolized by the liver.
Orally administered cocaine takes approximately 30 minutes to enter the bloodstream.
Typically, only a third of an oral dose is absorbed, although absorption has been shown to reach 60% in controlled settings.